Risk of Death from Cardiovascular Disease

Consumption of Grain Based

Dietary Fiber May Reduce

Risk of Death from

Cardiovascular Disease

Dietary fiber specifically from grain sources may reduce the risk of death from cardiovascular, infectious, and respiratory diseases, according to a new US study.

US researchers based at the National Cancer Institute in Maryland and the AARP in Washington DC concluded that dietary fiber from grains was inversely related to total and cause-specific death in both men and women.

Such fiber intake, they reported, also lowered the risk of death from cardiovascular, infectious, and respiratory diseases by 24 per cent to 56 per cent in men and by 34 per cent to 59 per cent in women.

Moreover, the authors found that inverse association between dietary fibre intake and cancer death was

observed in men, but not in women.

The researchers argue that while dietary fiber has been hypothesized to lower the risk of coronary heart disease, diabetes, and some cancers little is known of the effect of dietary fiber intake on total death and cause-specific deaths.

They stressed that "previous studies examining the association between dietary fibre and mortality were

limited by small sample sizes, narrow ranges of dietary fiber intakes, and inadequate control for confounding,

leading to decreased power, intakes without the necessary ranges to observe associations, and residual


The research team explained their objective thus was to investigate dietary fibre intake in relation to total and

cause-specific mortality in a large prospective cohort of men and women in the US based NIH (National

Institutes of Health) -AARP Diet and Health Study, in which more than 30,000 deaths occurred during an

average of 9 years of follow-up and a wide range of dietary intakes.

The researchers said that diet was assessed using a food-frequency questionnaire at baseline. Cause of

death was identified using the National Death Index Plus. Cox proportional hazard models were used to estimate relative risks and 2-sided 95 per cent confidence intervals (CIs).

"We also collected demographic, anthropometric, and lifestyle information, including history of smoking, physical activity, family history of cancers, menopausal hormone therapy use in women, and some medical conditions at baseline," they said, adding that they performed sex-specific analysis and reported the results by sex.


The authors concluded that dietary fiber intake was associated with a significantly lowered risk of total death

in both men and women.

Comparing the lowest quintile of dietary fiber intake, both men and women in the highest quintile had a 22 percent lower risk of total death, they reported.

Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.

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