Risk of Death from Cardiovascular Disease
Consumption of Grain Based
Dietary Fiber May Reduce
Risk of Death from
Dietary fiber specifically
from grain sources may
reduce the risk of death
infectious, and respiratory
diseases, according to a
new US study.
US researchers based at the National Cancer Institute
in Maryland and the AARP in Washington DC concluded
that dietary fiber from grains was inversely related to total
and cause-specific death in both men and women.
Such fiber intake, they reported, also lowered the risk
of death from cardiovascular, infectious, and respiratory
diseases by 24 per cent to 56 per cent in men and by
34 per cent to 59 per cent in women.
Moreover, the authors found that inverse association
between dietary fibre intake and cancer death was
observed in men, but not in women.
The researchers argue that while dietary fiber has been
hypothesized to lower the risk of coronary heart disease,
diabetes, and some cancers little is known of the effect
of dietary fiber intake on total death and cause-specific
They stressed that "previous studies examining the
association between dietary fibre and mortality were
limited by small sample sizes, narrow ranges of dietary
fiber intakes, and inadequate control for confounding,
leading to decreased power, intakes without the
necessary ranges to observe associations, and residual
The research team explained their objective thus was
to investigate dietary fibre intake in relation to total and
cause-specific mortality in a large prospective cohort of
men and women in the US based NIH (National
Institutes of Health) -AARP Diet and Health Study, in
which more than 30,000 deaths occurred during an
average of 9 years of follow-up and a wide range of
The researchers said that diet was assessed using
a food-frequency questionnaire at baseline. Cause of
death was identified using the National Death Index Plus.
Cox proportional hazard models were used to estimate
relative risks and 2-sided 95 per cent confidence
"We also collected demographic, anthropometric, and
lifestyle information, including history of smoking, physical
activity, family history of cancers, menopausal hormone
therapy use in women, and some medical conditions
at baseline," they said, adding that they performed
sex-specific analysis and reported the results by sex.
The authors concluded that dietary fiber intake was
associated with a significantly lowered risk of total death
in both men and women.
Comparing the lowest quintile of dietary fiber intake, both
men and women in the highest quintile had a 22 percent
lower risk of total death, they reported.
Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.
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